to study the effect of oxygen supplementation to reduce the surgical wound infections in abdominal surgeries.

to study the effect of perioperative oxygen supplementation to reduce the incidence of surgical site infections in patients undergoing elective major abdominal surgeries - a randomised control study.

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/02/031436

Enrollment

Registered

2021-02-22

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C185- Malignant neoplasm of splenic flexure

Interventions

Intervention1: PERIOPERATIVE OXYGEN SUPPLIMENTATION: After the induction of anaesthesia and endotracheal intubation, each patient will be assigned to one of two groups through the use of a set of seal

the second group (Groupâ??B) will receive 80 percent oxygen and 20 percent nitrous oxide. The first group (Group-A) will receive 30% (28-35%) FiO2 in post-operative period for two hours at a flow rate

upper respiratory tract infection, urinary tract infection, anastomotic integrity, intensive care unit (ICU) stay, length of Hospital Stay (LoHS) and the need for postoperative interventions including

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients eligible to give valid consent for the study. 2. Patients undergoing all types of elective major abdominal surgeries including upper gastrointestinal, hepato-pancreato-biliary and lower gastrointestinal like colorectal surgeries.

Exclusion criteria

Exclusion criteria: 1. Immunocompromised patients including poorly controlled diabetes mellitus, patient on long standing steroids. 2. Patient having comorbidities including severe COPD, severe Bronchial Asthma, or any chronic interstitial lung diseases. 3. Patients with any Percutaneous intraabdominal drainage catheter in situ with positive culture report. 4. Patient who receives antibiotic or antiseptic irrigation (IOPL) of the wound or peritoneal cavity during intraoperative period.

Design outcomes

Primary

Measure	Time frame
TO SEE THE REDUCE INCIDENCE OF SURGICAL SITE INFECTIONS IN MAJOR ABDOMINAL SURGERIES.Timepoint: TILL 4 WEEKS	—

Secondary

Measure	Time frame
To see other morbidities; upper respiratory tract infection, urinary tract infection, anastomotic integrity, intensive care unit (ICU) stay, length of Hospital Stay (LoHS) and the need for postoperative interventions including surgery and mortality.Timepoint: TILL 4 WEEKS	—

Countries

India

Contacts

Public ContactNILADRI MOHAN RAYPATTANAIK

POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH

kamanlil@yahoo.com7087009644

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026