Treatment Of Periodontal Intrabony Defects Using Advanced - Platelet Rich Fibrin With And Without Intra Marrow Penetration

Advanced Platelet Rich Fibrin With and Without Intra Marrow Penetration in the Treatment of Periodontal Intrabony Defects: A Randomised Control Trial

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/02/031432

Enrollment

Registered

2021-02-22

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: intra marrow penetration and advanced platelet rich fibrin: advanced platelet rich fibrin Intervention2: advanced platelet rich fibrin: Advanced Platelet Ã¢â?¬â?? Rich Fibrin (A-PRF) is

Eligibility

Inclusion criteria

Inclusion criteria: Age group of 22 to 60 years. Probing pocket depth Ã¢â?°Â¥ 5mm. Clinical attachment loss Ã¢â?°Â¥3mm. Presence of 2-3 walled defect with radiographic depth > 4mm

Exclusion criteria

Exclusion criteria: Systemically compromised patients. Patients who are on medications that could interfere with wound healing. Patients with grade III mobility. Chronic smokers and alcoholics. Pregnant and lactating females. Patients who had undergone periodontal surgery with in a period of last 1 year.

Design outcomes

Primary

Measure	Time frame
To evaluate and compare clinical and radiographic outcome of Open Flap Debridement (OFD) and Advanced - Platelet Rich Fibrin (A-PRF) with and without Intra Marrow Penetration (IMP) in the treatment of periodontal intrabony defectsTimepoint: baseline, 3 months and 6 months post operatively	—

Secondary

Measure	Time frame
To evaluate the clinical and radiographic outcome of OFD and A-PRF with IMP in the treatment of periodontal intrabony defects. To evaluate the clinical and radiographic outcome of OFD and A-PRF alone in the treatment of periodontal intrabony defects. To compare and correlate the differences in the clinical and radiographic outcome of OFD and A-PRF with and without IMP. Timepoint: baseline, 3 months and 6 months post operatively	—

Measure

Time frame

To evaluate the clinical and radiographic outcome of OFD and A-PRF with IMP in the treatment of periodontal intrabony defects. To evaluate the clinical and radiographic outcome of OFD and A-PRF alone in the treatment of periodontal intrabony defects. To compare and correlate the differences in the clinical and radiographic outcome of OFD and A-PRF with and without IMP. Timepoint: baseline, 3 months and 6 months post operatively

—

Countries

India

Contacts

Public ContactParth Sharma

institute of dental sciences

drmanju75@rediffmail.com8126644491

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026