Health Condition 1: K720- Acute and subacute hepatic failure Health Condition 2: T604- Toxic effect of rodenticides
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Amrita institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: Patients having acute liver failure
Exclusion criteria
Exclusion criteria: Age less than 18 Hemodynamics instability
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the sensitivity of resistive index to predict onset of severe encephalopathy ( grade 3 or intubation ) by 48 hours in.adult acute liver failure patientsTimepoint: Daily , for 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the sensitivity of Resistive Index (RI) to predict onset of severe encephalopathy (Grade 3 or above, or intubation) by 72 hours in adult Acute Liver Failure (ALF) patientsTimepoint: 72 hours;. To evaluate the sensitivity of Pulsatility Index (PI) to predict onset of severe encephalopathy (Grade 3 or above, or intubation) by 72 hours in adult Acute Liver Failure (ALF) patients.Timepoint: 72 hours;To evaluate other indices like Pulsatility Index (PI) to predict onset of severe encephalopathy (Grade 3 or above, or intubation) by 48 hours in adult Acute Liver Failure (ALF) patients. Timepoint: 48 hours;To evaluate the correlation of arterial ammonia with degree of encephalopathyTimepoint: 72 hours;To evaluate the correlation of the RI, PI and arterial ammonia to grade of encephalopathy as the patient recovers, in those who recover either spontaneously or after liver transplantationTimepoint: NA | — |
Countries
India
Contacts
Public ContactK SINDHUJA
Amrita institute of medical sciences
Outcome results
None listed