To evaluate the effect of reduction in thickness of uterine cavity lining on pregnancy outcome

Endometrial compaction and its impact on pregnancy rate in frozen embryo transfer cycle

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2021/02/031397

Enrollment

1000

Registered

2021-02-18

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N979- Female infertility, unspecified

Interventions

Intervention1: none- its an observational study: none- its an observational study

Eligibility

Inclusion criteria

Inclusion criteria: 1.Women undergoing frozen embryo transfer with HRT protocol for endometrial preparation 2.Endometrial thickness more than or equal to 8mm on day of starting progesterone

Exclusion criteria

Exclusion criteria: 1.Endometrial preparation with natural/modified natural cycle 2.Thin endometrium (less than 8 mm on day of progesterone administration) 3.Cases with only poor quality embryo 4.Women with congenital and untreated acquired uterine anomaly 5.Women with thrombophilia 6.Women with untreated hydrosalpinx 7.Couple with genetic and chromosomal abnormality 8.Women with BMI >/30 9.Uncontrolled endocrine or haematological dysfunction 10.Women undergoing PGT cycles 11.Those who had difficult embryo transfer in the index cycle

Design outcomes

Primary

Measure	Time frame
Ongoing pregnancy rate/Live Birth rateTimepoint: 20 weeks	—

Secondary

Measure	Time frame
beta hCG positive rate Clinical pregnancy rate Miscarriage rate Timepoint: 4-6 weeks,	—

Countries

India

Contacts

Public ContactDr Noushin Abdul Majiyd

Craft Hospital and Research Centre

drnoshinashraf@gmail.com9544240002

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026