A clinical trial to study the effect of madhu(honey) kumari(aloe vera) in the management of under eye dark circles

A randomized controlled clinical study to evaluate the efficacy of madhu kumari lepa in management of periorbital hyperpigmentation

Status

Recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/02/031395

Enrollment

Registered

2021-02-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L80-L99- Other disorders of the skin and subcutaneous tissue

Interventions

Intervention1: Madhu kumari lepa: A folklore practice, external application of cost effective and easily available drugs for beautification and cosmetic purpose ,madhu (honey)+ kumari(aloevera) , subj

Eligibility

Inclusion criteria

Inclusion criteria: 1.subjects diagnosed with periorbital hyperpigmentation will be included 2.subjects of age group 21 to 50 years will be included irrespective of their gender ,religion,and socio economic status 3.subjects who are willing to participate in the study 4.subjects with periorbital hyperpigmentation caused due to constitutional causes

Exclusion criteria

Exclusion criteria: 1.subjects taking photosensitizing drugs like NASIDS,anti -histamines,oral contraceptives,sulphonamides etc 2.Chloasma/melasma,post -inflammatory hyperpigmentation will be excluded 3.smoking ,alcoholism 4.anemia 5.subjects suffering from any other systemic illness

Design outcomes

Primary

Measure	Time frame
1.to evaluate the effect of madhu kumari lepa in periorbital hyper pigmentation 2.to re-evaluate the effect of conventional topical cream (unishade plus)for periorbital hyperpigmentation 3.to compare the efficacy of madhu kumari lepa with conventional topical creamTimepoint: Pre -Study assessment-0 day 1st assessment -10th day 1st follow up-20th day 2nd follow up-30th day	—

Secondary

Measure	Time frame
reduced dryness of the skin,reduced puffiness and reduction in wrinklesTimepoint: 1.to evaluate the effect of madhu kumari lepa in periorbital hyper pigmentation 2.to re-evaluate the effect of conventional topical cream (unishade plus)for periorbital hyper pigmentation 3.to compare the efficacy of madhu kumari lepa with conventinal topical cream,the duration of treatment is for 10 days,assesment will be on 10th day and follow up will be done on 20th and 30 th day	—

Measure

Time frame

reduced dryness of the skin,reduced puffiness and reduction in wrinklesTimepoint: 1.to evaluate the effect of madhu kumari lepa in periorbital hyper pigmentation 2.to re-evaluate the effect of conventional topical cream (unishade plus)for periorbital hyper pigmentation 3.to compare the efficacy of madhu kumari lepa with conventinal topical cream,the duration of treatment is for 10 days,assesment will be on 10th day and follow up will be done on 20th and 30 th day

—

Countries

India

Contacts

Public ContactDrPURVA VERMA

sri sri college of ayurvedic science and research

sajithak96@gmail.com9448415810

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026