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ROLE OF TRANEXAMIC ACID IN REDUCING BLOOD LOSS IN VAGINAL DELIVERY

Evaluation of blood loss during active management of third stage of labour with and without tranexamic acid

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/031360
Enrollment
100
Registered
2021-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium

Interventions

Intervention1: Injection.Tranexamic acid 1gm: â?¢ 100 Pregnant women prior to induction and early labor will be examined by taking informed and written consent of the patient. â?¢ In each patient, t

Sponsors

Gamidi Anusha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Age > 19 years and 2) Spontaneous vaginal delivery 3) Induced vaginal delivery 4) Assisted vaginal delivery 5) Term > 35 weeks of gestation 6) Singleton pregnancy

Exclusion criteria

Exclusion criteria: 1) History of venous (deep vein thrombosis and/or pulmonary embolism) or arterial (angina pectoris,myocardial infarction, stroke) thrombosis 2) History of epilepsy or seizure 3) Any known cardiovascular, renal, or liver disorders 4) History of Autoimmune disease 5) History of Sickle cell disease 6) History of Severe hemorrhagic disease 7) Placenta previa 8) Abnormally invasive placenta (placenta accreta/increta/percreta) 9) Abruptio placentae 10) Eclampsia, HELLP syndrome 11) Multiple pregnancy 12) In utero fetal death 13) Administration of low-molecular-weight heparin or antiplatelet agents during the week before delivery 14) PROMâ??patients referred from periphery with PROM were excluded as the chances of chorioamnionitis were more due to repeated internal examinations 15) Prolonged and obstructed labour

Design outcomes

Primary

MeasureTime frame
Injection Tranexamic acid administration along with oxytocin can reduce obstetric blood lossTimepoint: 24 months

Secondary

MeasureTime frame
Injection tranexamic acid administration along with oxytocin can reduce obsetric blood lossTimepoint: 24 months

Countries

India

Contacts

Public ContactGamidi Anusha

Dr.pinnamaneni siddhartha institute of medical sciences

dr.gayathri.bhargav@gmail.com9440294421

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026