Is steroid nasal washing better than saline nasal washing after endoscopic nasal surgery?

Efficacy of budesonide nasal irrigation in comparison to normal saline nasal irrigation in post-operative management of endoscopic sinus surgery â?? a randomized control study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/02/031356

Enrollment

Registered

2021-02-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J339- Nasal polyp, unspecified

Interventions

Intervention1: Budesonide (0.5mg/2ml): Dose : (0.5mg/2ml) in 200ml saline as topical nasal irrigation (100ml each side of nose)

Cumulative dose : 1mg/day

Frequency : twice a day

Duration : 3 months

Route : Intra-nasal - topical irrigation. Control Intervention1: Normal saline (0.9%): Dose : 200ml (100ml each side of nasal cavity)

Frequency : twice daily

Route : Intra-nasal - topical irrigation.

Eligibility

Inclusion criteria

Inclusion criteria: >18years of age Those who undergo Endoscopic sinus surgery during the study period

Exclusion criteria

Exclusion criteria: Patients who are on concomitant use of oral steroids Patients having known hypersensitivity to corticosteroids Patients who had undergone CSF leak closure Allergic fungal sinusitis

Design outcomes

Primary

Measure	Time frame
Efficacy of the two arms compared by : SNOT 22 score Lund â?? Kennedy Endoscopic score SNOT 22 score â?? questionnaire filled in the presence of PI at each visit LKES score â?? calculated by two endoscopists . One â?? endoscopist in duty at scopy room on that day. Second â?? By Guide or co-investigator. Both scores are then averaged to arrive at the final score. Timepoint: 2 weeks and 3 months post op	—

Measure

Time frame

Efficacy of the two arms compared by : SNOT 22 score Lund â?? Kennedy Endoscopic score SNOT 22 score â?? questionnaire filled in the presence of PI at each visit LKES score â?? calculated by two endoscopists . One â?? endoscopist in duty at scopy room on that day. Second â?? By Guide or co-investigator. Both scores are then averaged to arrive at the final score. Timepoint: 2 weeks and 3 months post op

—

Secondary

Measure	Time frame
NOT APPLICABLETimepoint: NA	—

Countries

India

Contacts

Public ContactShameer Ahamed

Christian medical college, Vellore

reganupthomas@cmcvellore.ac.in9443211142

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026