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Variations in Optic Nerve Sheath diameter along with change in intra abdominal pressure and end tidal CO2 in laparoscopic surgery

A study to evaluate the effect of change in intra abdominal pressure and end-tidal CO2 on optic nerve sheath diameter in patients undergoing laparoscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/02/031333
Enrollment
60
Registered
2021-02-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

None listed

Sponsors

Department of Anaesthesiology and Critical Care JNMC AMU Aligarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) physical status I and II, scheduled to undergo elective surgery under general anaesthesia requiring tracheal intubation

Exclusion criteria

Exclusion criteria: (1)Patients having increased Intracranial pressure(ICP). (2)Any optic nerve disease or known orbital cavity tumor/malignancy (3)Known orbital injury or prior ocular surgery (4)History of neurological disorders, hyperthyroidism. (5)Pregnant/lactating female patient.

Design outcomes

Primary

MeasureTime frame
To observe the changes in Optic Nerve Sheath Diameter(ONSD) using USG following acute elevations of IAP and simultaneous changes in end-tidal CO2 Timepoint: The changes in ONSD will be measured with the corresponding changes in IAP, end-tidal CO2 and MAP during following time intervals after tracheal intubation and before the starting of surgical procedure, 5 mins after stabilisation of intra abdominal pressure of 10mm of Hg and 15mm of Hg and 10 mins after desufflation of gas. Further, the changes in ONSD corresponding to changes in IAP will be measured after standardizing/bringing the End-tidal CO2 to normal level(35-40 mm Hg)—

Secondary

MeasureTime frame
To observe changes in Mean Arterial Pressure(MAP) intraoperatively during acute elevations of IAP. To identify which is more sensitive parameter between End-tidal CO2 and Intra-abdominal pressure(IAP) on the ONSD. Timepoint: The changes in ONSD will be measured with the corresponding changes in IAP, end-tidal CO2 and MAP during following time intervals after tracheal intubation and before the starting of surgical procedure, 5 mins after stabilisation of intra abdominal pressure of 10mm of Hg and 15mm of Hg and 10 mins after desufflation of gas. Further, the changes in ONSD corresponding to changes in IAP will be measured after standardizing/bringing the End-tidal CO2 to normal level(35-40 mm Hg)—

Countries

India

Contacts

Public ContactAnjali Kumari

Jawaharlal Nehru Medical College, Aligarh Muslim UniversityÂ

sma99@rediffmail.com9897454739

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026