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Cardiac dysfunction in head injury patients

Cardiac dysfunction in moderate to severe traumatic brain injury patients undergoing conservative management versus surgical decompression: A cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/02/031312
Enrollment
264
Registered
2021-02-16
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S062- Diffuse traumatic brain injury Health Condition 2: S063- Focal traumatic brain injury Health Condition 3: S066- Traumatic subarachnoid hemorrhage Health Condition 4: S065- Traumatic subdural hemorrhage

Interventions

None listed

Sponsors

Department of Anesthesia and Intensive Care PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. GCS

Exclusion criteria

Exclusion criteria: 1. Patients above 65 or less than 18 years of age 2. Patients with significant extracranial injury (AIS more than 4) 3. Moribund patients with GCS less than 5 who are not expected to survive beyond 48 h 4. Patients with medical history of cardio-thoracic surgery or significant cardiovascular events (stroke, coronary artery disease, myocardial infarction, pacemaker, atrial fibrillation, or congestive heart disease) and patients with traumatic hemorrhagic shock.

Design outcomes

Primary

MeasureTime frame
Incidence of systolic dysfunction recorded after 72 hours of enrollmentTimepoint: after 72 hours of enrollment—

Secondary

MeasureTime frame
30 days mortality rate in severe TBI patients with or without cardiac dysfunctionTimepoint: 30 days;ââ?¬Â¢ Change in Cardiac Troponin I levels from baseline on day 3 following injuryTimepoint: after 72 hrs;Changes in ECG findings from baseline on day 3 following injuryTimepoint: after 72 hrs;Correlation between NCCT findings and incidence of cardiac dysfunctionTimepoint: within 48 hrs;Incidence of baseline cardiac dysfunction following TBI (includes LV systolic and diastolic dysfunction, right ventricular (RV) dysfunction and RWMA)Timepoint: Date of admission;Incidence of late onset cardiac dysfunction (more than 48 h of injury)Timepoint: within 7 days;Time for peak recovery from LV systolic dysfunctionTimepoint: within 7 days;Time for significant recovery from LV systolic dysfunctionTimepoint: with in 7 days—

Countries

India

Contacts

Public ContactDr Jeetinder Kaur Makkar

Postgraduate Institution of Medical Education and Research

jeet1516@gmail.com8847288105

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026