Health Condition 1: C50- Malignant neoplasm of breast
Conditions
Interventions
Intervention1: intra op and post op topical tranexamic acid.: In addition to the single intra operative dose, 5 doses of 20 ml of25mg/ml Tranexamic acid will be given through the drain daily for 5 day
Sponsors
post graduate institute of medical education and research
Eligibility
Inclusion criteria
Inclusion criteria: • Female patients of age >18 years Biopsy proven breast cancer undergoing ALND, Willing to join study
Exclusion criteria
Exclusion criteria: -Age -ASA grade IV or more. -Patients undergoing Immediate Breast Reconstruction. -Patients with prior radiotherapy. -Patients already on anti-coagulants or fibrinolytics. -Patients who have undergone previous ALND or any axillary surgery -Previous history of thromboembolic disease (deep vein thrombosis, pulmonary embolism, varicose veins, cerebrovascular accidents).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total duration of axillary drainage Total volume of axillary drainage Timepoint: 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| -Daily drain output -Wound infection -Seroma formation -Number of aspirations for seroma Safety analysis Timepoint: 21 days | — |
Countries
India
Contacts
Public ContactDR ISHITA LAROIYA
Post-Graduate Institute of Medical Education and Research
Outcome results
None listed