FindTrial
Sign In

Finding the risk factors for preterm brain injury called periventricular leucomalacia to decide on MRI or ultrasound scan in premature infants

Determination of predictors of periventricular leucomalacia to formulate a risk-factor based neuroimaging strategy in very preterm infants â?? A retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/02/031226
Enrollment
1400
Registered
2021-02-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G801- Spastic diplegic cerebral palsy

Interventions

Intervention1: None: None

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Preterm infants < 32 weeksâ?? gestation admitted in NICU between 2013 and 2020

Exclusion criteria

Exclusion criteria: • Neuroimaging (magnetic resonance imaging, MRI or USG cranium) beyond 2 weeks of life not available • Infants with neuroimaging showing brain malformations/ other pathologies

Design outcomes

Primary

MeasureTime frame
Risk factors of PVL from univariate analysis followed by multivariate analysisTimepoint: From birth until discharge—

Secondary

MeasureTime frame
Inter-relationship among predictor variables will be analyzed, wherever applicableTimepoint: From birth until discharge;Strength of association between predictor and PVL using adjusted odds ratio (aOR)Timepoint: From birth until discharge—

Countries

India

Contacts

Public ContactThangaraj Abiramalatha

Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai

abi_paeds@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026