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Comparison between Nano Biofusion gel and Chlorhexidine gel along with normal teeth cleaning procedures in Severe form of Gum disease

Comparative Evaluation of NanoBiofusion gel(NBF GEL) and Chlorhexidine gel as an adjunct to Scaling and root planing in the treatment of Chronic Periodontitis: A Clinico Microbiological study

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/031173
Enrollment
75
Registered
2021-02-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: NBF GEL: Dosage form : Gel adults- pea sized gel Route of administration: deep gingival sulcus( periodontal pockets ) through blunt cannula Frequency and duration of therapy : baseline

Sponsors

ABRAHAM DAVIS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients willing to participate in the study. 2. Patients aged between 30-60 years. 3. Patients with good general health, suffering from chronic generalized/Localized periodontitis with a minimum of twenty teeth present. 4. Periodontal pocket of Probing depth of 4-6mm classified as localized/generalized chronic periodontitis. 5. Patients who had not received any periodontal treatment in the past 6 months.

Exclusion criteria

Exclusion criteria: 1. Patients on chemical/herbal drugs for the past 3 months 2. Periodontal therapy received in past 6 months 3. Use of Systemic or subgingival antimicrobial within the 6 months prior to the study 4. Use of Ant inflammatory therapy within the 6 months prior to the study 5. Allergy to CHX 6. Habit of Tobacco chewing and smoking 7. History of Systemic diseases that could influence the course of Periodontal disease or would require prophylactic antibiotics (not medically compromised) 8. Pregnancy and lactation 9. Aggressive periodontitis

Design outcomes

Primary

MeasureTime frame
Periodontal pocket reductionTimepoint: 12 weeks

Secondary

MeasureTime frame
Antimicrobial efficacyTimepoint: 6 weeks

Countries

India

Contacts

Public ContactAbraham Davis

AJ INSTITUTE OF DENTAL SCIENCES

nandinimanjunath@ymail.com9845314069

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026