The aim of the study is to compare the difference between two treatment techniques , with and without curcumin gel application along with teeth cleaning procedures in diabetic population with associated tooth- gum related problems

Comparative assessment of IL 6 leves in diabetic patients with chronic localized periodontitis treated with scaling and root planing with and without 2 % curcumin gel- a clinical study

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/02/031169

Enrollment

Registered

2021-02-10

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: 2 % Curcumin gel: Local drug delivery, 0.5 -1ml of 2 % curcumin gel which will be deposited into the sulcus ( periodontal pocket) with the help of a 2ml blunt syringe on day 1, on 1oth

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients willing to participate in the study 2.Subjects with Age group of 30 to 60years. 3.Patients with chronic localized periodontitis. 4.Patients should have pockets measuring less than 5mm (4-5mm) 5.Patients with type 2 diabetic mellitus 6.Patients who are able to follow verbal or written instructions.

Exclusion criteria

Exclusion criteria: 1.Patients with systemic disorders (Myocardial infarction, musculoskeletal diseases and trauma ) 2. Patients with Hba1c levels >7% 3.Patients under antibiotics, anticoagulants, steroids, hormonal therapy and also patient who underwent periodontal treatment in past 6 months 4.Pregnant patients and lactating mothers. 5.Patients with habit of tobacco chewing, smoking, alcohol consumption 6.Patients with severe chronic periodontitis and Aggressive periodontitis 7.Patients with acute intraoral lesions

Design outcomes

Primary

Measure	Time frame
periodontal pocket reduction, reduction in IL 6 levelTimepoint: 3 months	—

Secondary

Measure	Time frame
reduction in HbA1c levelsTimepoint: 3 months	—

Countries

India

Contacts

Public ContactDr Grace Mary Joseph

AJ INSTITUTE OF DENTAL SCIENCES

parikodgi76@gmail.com9448915650

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026