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To Study Correlation Of Two Blood Gas Analysis Derived Parameters, Veno-Arterial Carbon Dioxide Pressure Difference To Arterio-Venous Oxygen Content Difference Ratio With Lactate Clearance Rate During Early Resuscitation In Septic Shock Patients

Correlation Of Veno-Arterial Carbon Dioxide Pressure Difference To Arterio-Venous Oxygen Content Difference Ratio With Lactate Clearance Rate For Early Resuscitation Goal In Patients Of Septic Shock

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/02/031158
Enrollment
55
Registered
2021-02-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B948- Sequelae of other specified infectious and parasitic diseases

Interventions

None listed

Sponsors

ABVIMS DR RAM MANOHAR LOHIA HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: > 18 yrs Admitted in ICU for more than 24 hrs for both medical or surgical disease with septic shock

Exclusion criteria

Exclusion criteria: 1 Refusal of Consent 2 Drop out during sampling period 3 Pregnant females 4 Liver Cirrhosis child Pugh C 5 End stage renal disease 6 Sustained hemodynamic unstable Cardiac arrhythmias or LVEF 7 Severe COPD (grade 3&4)

Design outcomes

Primary

MeasureTime frame
1. To determine correlation between Veno-arterial carbon dioxide pressure difference to arterio-venous oxygen content difference (Pcv-aCo2/Ca-cvO2) ratio and lactate clearance rate (T24) for early resuscitation goal in septic shock patientsTimepoint: 24 hrs—

Secondary

MeasureTime frame
1. To determine Correlation between Pcv-aCo2/Ca-cvO2 ratios (T24) with lactate levels, Scvo2, Pv-aCo2 clearance 2. To determine ability of Pcv-aCo2/Ca-cvO2 ratio (T24) to predict 28 days mortality and organ dysfunction using SOFA score at day 3 3. To determine incidence of 28 day mortalityTimepoint: 28 days—

Countries

India

Contacts

Public ContactDR DEEPEISH GUPTA

ABVIMS & DR RML HOSPITAL

dr.deepeish@gmail.com01123404699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026