Health Condition 1: P073- Preterm [premature] newborn [other]
Conditions
Interventions
Intervention1: SMOFLipid®: SMOFLipid is a intravenous lipid emulsion to be given in standard doses 1-3.5 g/kg/day via iv route and daily 24 hours infusion
Duration as per standard unit protocol ( us
Sponsors
Institue Research Grant
Eligibility
Inclusion criteria
Inclusion criteria: 1.Preterm neonates 2.Initiated on parenteral nutrition including lipids (at least 1 g/kg/day) in first three days of life 3.Anticipated to receive parenteral nutrition for at least 5 days â?? e.g. neonates
Exclusion criteria
Exclusion criteria: Neonates with major congenital malformation and hydrops will be excluded from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to regain birth weight in daysTimepoint: daily weight will be taken till birth weight is regained | — |
Secondary
| Measure | Time frame |
|---|---|
| Catalase, Superoxide Dismutase and Glutathione PeroxidaseTimepoint: Day 0 and day 7;Fatty acid profile by HPLCTimepoint: Day 0 and day 7;Hypertriglyceridemia more than 265 mg/dlTimepoint: Day 0 and day 7;Parenteral Nutrition Associated Liver Disease defined as direct bilirubin more than 2 mg/dlTimepoint: 2 weeks;Retinopathy of PrematurityTimepoint: 4 weeks as per unit protocol;Weekly head growth in first 4 weeksTimepoint: Weekly for first 4 weeks;Weekly weight gain in first 4 weeksTimepoint: Weekly for first 4 weeks | — |
Countries
India
Contacts
Public ContactMd Tousifullah
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed