Health Condition 1: I468- Cardiac arrest due to other underlying condition
Conditions
Interventions
Intervention1: Hydrocortisone: IV 100mg stat within 3 minutes of starting of CPR followed by 100mg IV 8 hourly for 24 hours.
Control Intervention1: Placebo (0.9% Nacl): IV 5ml stat within 3 mins of st
Sponsors
Department of emergency medicine All India Institute of Medical Sciences New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Adults more than 18 years receiving CPR in department of emergency medicine.
Exclusion criteria
Exclusion criteria: 1.Traumatic 2.Prearrest IV steroid intake 3.Active upper GI bleed 4.Verbal consent not given by relatives 5.Patients showing signs of irreversible Cardiac arrest at presentation or where cardiopulmonary resuscitation cannot be done: a. Decapitation b. Decomposition c. Post-mortem lividity d. Post-mortem rigidity e. Burned beyond recognition f. Complete crush injury of thorax
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Return of spontaneous circulation (Sustained for more than 20 minutes)Timepoint: 20 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| SurvivalTimepoint: 24 hours;Favorable neurological outcome as per Cerebral Performance Categories (CPC) Score.Timepoint: At 7 days or at discharge, whichever is earlier.;Safety end points : 1. GI bleed 2. Hyperglycemia 3. InfectionTimepoint: At 7 days or at discharge, whichever is earlier. | — |
Countries
India
Contacts
Public ContactDr Golak Prasad Patra
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed