Health Condition 1: C50- Malignant neoplasm of breast
Conditions
Interventions
Intervention1: Dexmedetomidine-Lignocaine infusion
: Opioid free anaesthesia using Dexmedetomidine 1 mcg/kg IV bolus over 10 minutes before induction and
0.5 mcg/kg/h IV infusion as maintenance
And
Li
Sponsors
ANNU JOSE
Eligibility
Inclusion criteria
Inclusion criteria: Patients with American Society of Anaesthesiologists (ASA) physical status I or II undergoing modified radical mastectomy surgery. Age 18 â?? 65 years BMI between 18 and 30
Exclusion criteria
Exclusion criteria: Patient refusal Pregnant and breastfeeding Patient on beta-blocker Patient with AV nodal block Patient with autonomic dysfunction Patient with chronic pain on opioids or other analgesics History of allergy to study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamics, in the form of heart rate, systolic, diastolic, and mean arterial blood pressure, on induction and the surgery thereafterTimepoint: Before induction till surgery is over | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative anaesthetic requirement Recovery profile Any recall of events in intraoperative period Timepoint: 24 hours postop | — |
Countries
India
Contacts
Public ContactANNU JOSE
Government medical college Kozhikode
Outcome results
None listed