FindTrial
Sign In

Comparison of add on drugs Dexmedetomidine and Fentanyl to Ropivacaine in pregnant patients undergoing cesarean section

COMPARISON OF EFFICACY OF INTRATHECAL DEXMEDETOMIDINE VERSUS FENTANYL AS ADJUVANT TO ISOBARIC ROPIVACAINE IN PARTURIENTS UNDERGOING ELECTIVE LSCS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/031038
Enrollment
60
Registered
2021-02-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Isobaric Ropivacaine with Dexmedetomidine: in parturients undergoing elective lscs to assess sensory and motor blockade and duration of analgesia Control Intervention1: Isobaric Ropivac

Sponsors

Dr Ashna Shetty
Lead Sponsor
Dr Madhumala
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Parturients of age group 18-35 years undergoing elective lower segment caesarean section under subarachnoid block. 2. Parturients willing to give written informed consent[annexure 1(a)] 3. Parturients belonging to ASA II[annexure 3(a)]

Exclusion criteria

Exclusion criteria: 1. Patients undergoing emergency lower segment caesarean section under subarachnoid block 2. Patients with medical and obstetric complications like anaemia , heart diseases , gestational hypertension, gestational diabetes , shock, septicaemia and hypertension 3. Patients not willing to give consent . 4. Patients with history of hypersensitivity to local anaesthetic, Dexmedetomidine , Fentanyl 5. Subjects having any absolute contraindications for spinal anaesthesia like increased ICP, severe hypovolemia , bleeding diathesis , local infection 6. Patients with height 170 cm and BMI >30

Design outcomes

Primary

MeasureTime frame
1. Sensory blockade with respect to onset , maximum level attained , time taken for attainment of maximum level , time taken for two segments sensory regression and total duration of sensory blockade 2. Motor blockade with respect to onset , maximum level , time taken for attainment of maximum level, quality of motor blockade and total duration of motor blockade 3. Total duration of analgesia Timepoint: 4 hours—

Secondary

MeasureTime frame
4. Neonatal APGAR scores 5. Adverse effects like nausea , vomiting , desaturation, hypotension ,bradycardia and excessive sedation.Timepoint: 60 minutes—

Countries

India

Contacts

Public ContactDr Madhumala

Bangalore Medical College and Research Institute

drmadhumala@gmail.com9886786768

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026