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Perineural invasion in oral squamous cell carcinoma.

Perineural invasion and nerve morphometry in oral squamous cell carcinoma and their correlation with other prognostic markers â?? A cross-sectional study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/02/031037
Enrollment
58
Registered
2021-02-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

Interventions

Intervention1: Perineural invasion: PNI is a form of tumor spread exhibited by malignancies which are neurotropic in nature and correlates with aggressive behavior, disease reccurence and mortality. I

Sponsors

Rohilkhand Medical College Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Biopsies from oral cavity diagnosed microscopically as oral squamous cell carcinoma during the study period.

Exclusion criteria

Exclusion criteria: Cancers of oral cavity other than squamous cell carcinomas. Inadequate biopsy specimen.

Design outcomes

Primary

MeasureTime frame
Perineural invasion, nerve morphometry and immunohistochemistry in oral squamous cell carcinoma.Timepoint: Nil—

Secondary

MeasureTime frame
Patterns of PNI on microscopy along with measurement of nerve tumor distance and nerve diameter in PNI negative tumors on S100 stained slides.Timepoint: Nil—

Countries

India

Contacts

Public ContactPrateek Sharma

Rohilkhand Medical College & Hospital, Bareilly

dr.mithila@gmail.com7906080213

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026