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Post operative agitation and hyperactivity in children can be reduced by dexmedetomidine and propofol-which is better

Comparison of incidence of emergence delirium in paediatric patients undergoing general anaesthesia using Propofol and Dexmedetomidine: A randomized comparative open label trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/030983
Enrollment
80
Registered
2021-02-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: General Anaesthesia under inhalational agent sevoflurane: Comparative Drugs Propofol or Dexmedetomidine will be given before extubation and their effect on emergence delirium will be as

Sponsors

Dr S N Medical College Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 2 to 6 years of either gender of ASA PS I and II undergoing surgery under general anaesthesia with sevoflurane lasting less than 120min

Exclusion criteria

Exclusion criteria: 1.Parentsâ?? refusal. 2.Patients posted for elective surgery under regional anaesthesia. 3.ASA III and IV 4.Patients with active URI. 5.Patient with history of previous psychiatric illness. 6.Patients with a history of developmental delay 7.Patients having congenital airway problems, cardiac disorders or syndromic babies 8.Patients having psychological disorders, epilepsy and allergy to the study medications 9.Surgeries lasting for more than 120 min 10.Surgeries requiring endotracheal tube insertion for securing the airway

Design outcomes

Primary

MeasureTime frame
To compare the incidence of emergence delirium in subjects receiving propofol or dexmedetomidine at the end of surgery with sevoflurane anaesthesia during a period of six months.Timepoint: 30 min

Secondary

MeasureTime frame
To compare the hemodynamic parameters (HR, SBP, DBP, MAP, RR, SpO2, and ECG), sedation level, recovery time and post-operative pain between groups receiving propofol and dexmedetomidine.Timepoint: 30 min

Countries

India

Contacts

Public ContactDr Sarita Janweja

Dr S N Medical College Jodhpur

sarita.janweja@gmail.com9829116420

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026