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Study to compare the effectiveness of 15% trichloroacetic acid peel and 35% glycolic acid peel in the treatment of acanthosis nigricans

Efficacy of 15% trichloroacetic acid peel versus 35% glycolic acid peel in acanthosis nigricans - a randomized open label study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/030952
Enrollment
40
Registered
2021-02-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L83- Acanthosis nigricans

Interventions

Intervention1: Chemical Peel: 15% Trichloroacetic Acid Peel will be used in group A. Peel is topically applied. 3 setting of peeling will be done at the interval of 2 weeks Intervention2: Chemical Pee

Sponsors

Lady Hardinge Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult population in the age group of 18 years and above with clinical diagnosis of acanthosis nigricans involving face or neck or elbow or any combination of these three presenting to dermatology outpatient department at Smt Sucheta Kriplani Hospital

Exclusion criteria

Exclusion criteria: â?? Pregnant and lactating females. â?? Hypersensitivity to peeling agent. â?? Skin infection at the site of acanthosis nigricans ( Herpes, pyoderma, folliculitis) â?? Individual prone to keloid formation â?? History of any topical application in last 4 weeks

Design outcomes

Primary

MeasureTime frame
â?? Proportion of patients with Physician Assessment Score (PAS) more than 2 in the two groups. â?? Improvement in mean ANASI Score in two groups.Timepoint: At baseline, 2, 4, 6, 8 weeks—

Secondary

MeasureTime frame
â?? Mean Patient Satisfaction Score after 3 sessions in the two groups.Timepoint: 4,6,8 weeks;â?? Proportion of patients experiencing adverse effects in two groups.Timepoint: 4, 6, 8 weeks—

Countries

India

Contacts

Public ContactRashmi Sarkar

Lady Hardinge Medical College

rashmisarkar@gmail.com9818244340

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026