A comparison of two methods of physiotherapy for treating lower limb lymphedema following treatment for women with genital organ cancers

Prospective randomized controlled study comparing the efficacy of manual lymphatic drainage and pneumatic compression therapy on secondary lower limb lymphedema in patients undergoing surgery and/or radiotherapy for gynaecological malignancies.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/02/030940

Enrollment

140

Registered

2021-02-02

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C53- Malignant neoplasm of cervix uteri Health Condition 2: C541- Malignant neoplasm of endometrium Health Condition 3: C56- Malignant neoplasm of ovary Health Condition 4: C51- Malignant neoplasm of vulva

Interventions

Intervention1: Pneumatic compression therapy: The Pneumatic Compression Therapy (PCT) consists of a pump that applies pressure to multiple individual chambers inside the garment (Lympha press optimal)

Eligibility

Inclusion criteria

Inclusion criteria: 1.Willing female subjects with biopsy proven gynaecological malignancies (Carcinoma of endometrium, Carcinoma of cervix, Carcinoma of ovary and Carcinoma of vulva) undergoing curative surgery and or radiotherapy at SVIMS, Tirupati will be included for the estimation of incidence of lymphedema. Of these women who develop lymphedema will be included 2. Age between 30-65 years 3. Grade â?? 1 to 3 lymphedema (Annexure 2)

Exclusion criteria

Exclusion criteria: 1.Patients who are not willing to participate in the study 2.Age below 30 and above 65 years 3.Primary lymphedema or secondary lymphedema of different etiology at the time of diagnosis 4.Patients with past history of treatment for any cancer including gynaecological cancer, metastatic cancer, unilateral or bilateral amputation. 5.Grade â?? 4 lymphedema excluded. 6.Patients who are undergoing surgery for gynaecological malignancies without pelvic lymph node resection. 7.Patients who have had prior lower extremity vascular surgery. 8.Patients with past history of chronic lower limb swelling.

Design outcomes

Primary

Measure	Time frame
1 incidence of lymphedema in post gynaecological malignencies 2. Limb circumference measurement in centimetres Timepoint: 3 years	—

Secondary

Measure	Time frame
.VAS score in units 6. Quality of life score as per the questionnaire Timepoint: 3 years	—

Countries

India

Contacts

Public ContactRaghav Krishna S

Sri Venkateswar Institute of Medical Sciences

raghavasvims@gmail.com9885385150

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026