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Efficacy of analgesic patches with oral medication for surgical removal of mandibular third molars

Efficacy of pre-emptive analgesia with transdermal ketoprofen patches for surgical disimpaction of mandibular third molars

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/030924
Enrollment
54
Registered
2021-02-02
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Tab Ibuprofen: Tab Brufen 400mg given 30 min before procedure and post operatively as well Control Intervention1: Transdermal Ketoprofen patch: Ketoprofen transdermal patch 20mg applied

Sponsors

Rica Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged above 18 years of age requiring surgical disimpaction of lower third molars will be considered for the study. Patients volunteering to participate in the study and willing to come for follow up. Patients with no known history of allergy to NSAIDS and ketoprofen transdermal patches. The molars to be extracted should be asymptomatic and should be atleast partially bony impacted requiring bone removal.

Exclusion criteria

Exclusion criteria: Presence of local or systemic complications which may prevent or may lead to a delay in wound healing. Pregnant and lactating women. Patients on other medication which are known to have drug interactions or are contraindicated to use with NSAIDS

Design outcomes

Primary

MeasureTime frame
To assess the analgesic efficacy of pre-emptive analgesia on post operative pain following impacted third molar surgery.Timepoint: 1 week

Secondary

MeasureTime frame
1.Visual analog pain scale to measure pain intensity post operatively for 24 hours. 2.Pre op questionnaire during clinical interview to determine level of anxiety before the surgical procedure which is based on the modified dental anxiety scale.Timepoint: 24 hours

Countries

India

Contacts

Public ContactRica Singh

Manipal college of dental sciences ,Mangalore

arvind.r@manipal.edu9972517320

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026