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The study and comparison of occurrence of aberrrant salience (placing inappropriate significance to neutral events) in patients suffering from acute versus chronic Schizophrenia

Aberrant salience in acute vs chronic Schizophrenia: a cross sectional comparative study at a tertiary hospital in South India.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/02/030894
Enrollment
120
Registered
2021-02-01
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F20- Schizophrenia

Interventions

None listed

Sponsors

Department of Psychiatry
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Diagnosis of Schizophrenia and acute schizophrenia-like psychotic disorder (as per ICD 10 Diagnostic Criteria for Research) 2) those able to co-operate for the study

Exclusion criteria

Exclusion criteria: 1. Presence of comorbid axis I disorders 2. Presence of substance dependence (except tobacco) 3. Presence of intellectual impairment 4. Pregnant patients 5. Patients unwilling to take part in the study

Design outcomes

Primary

MeasureTime frame
Patients with acute schizophrenia will have higher levels of aberrant salience/higher blink rate/more cognitive deficits in comparison to chronic symptomatic patients of Schizophrenia, who in turn will have higher levels of aberrant salience/blink rate/more cognitive deficits in comparison to stable asymptomatic patients of Schizophrenia who will have higher levels of aberrant salience/cognitive deficits compared to healthy controlsTimepoint: 18 months

Secondary

MeasureTime frame
Patients with acute schizophrenia will have higher levels of aberrant salience/higher blink rate/more cognitive deficits in comparison to chronic symptomatic patients of Schizophrenia, who in turn will have higher levels of aberrant salience/blink rate/more cognitive deficits in comparison to stable asymptomatic patients of Schizophrenia who will have higher levels of aberrant salience/cognitive deficits compared to healthy controlsTimepoint: 6 months

Countries

India

Contacts

Public ContactDr Sonia Shenoy

Kasturba Medical College

soniashenoy22@gmail.com08202922217

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026