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Analgesic effect of oral pregabalin in patients undergoing urogenital surgeries under spinal anaesthesia

Analgesic effect of preemptive oral pregabalin in patients posted for urogenital surgeries under subarachnoid block- A randomized double blind interventional study at SMS Medical College and Attached Group of Hospitals, Jaipur during 2020-21

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/02/030888
Enrollment
60
Registered
2021-02-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N00-N99- Diseases of the genitourinary system

Interventions

Intervention1: Effect of preemptive oral 150mg pregabalin on postoperative pain relief: 30 patients will receive 150mg oral pregabalin 2 hours prior to surgery Intervention2: 150mg oral pregabalin cap

Sponsors

Department of anesthesiology SMS Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I & II. Undergoing elective urogenital surgeries under subarachnoid block

Exclusion criteria

Exclusion criteria: Patients not willing to participate in the study. ASA grade III and IV Cases with sepsis, bacteremia or skin infection of local site. History of severe hypovolemia, anemia and compromised renal, cardiac or respiratory status. Cases with raised intracranial tension. History of drug or alcohol abuse. History of taking gabapentin or pregabalin. History of taking opioid or sedative medications or with a history of psychiatric conditions. History of blood coagulopathies. Patient allergic to drugs used for study. Uncooperative patients. Failure of spinal anesthesia, cases in which general anesthesia will be required.

Design outcomes

Primary

MeasureTime frame
To determine the difference in mean time duration required for the need of first rescue analgesia between both the groups. Timepoint: To determine the difference in mean time duration required for the need of first rescue analgesia between both the groups specifically in first 24 hours—

Secondary

MeasureTime frame
To determine the difference in change in mean VAS score from baseline in both the groups To determine the difference in mean time duration for sensory and motor regression in both the groups. To determine the difference in percentage of cases who develop side effects in both the groups. Timepoint: The time duration of the study will be 2 hours prior to surgery to 24 hours after surgery—

Countries

India

Contacts

Public ContactDr Hardika Mangal

SMS Medical College Jaipur

rajnimathur@hotmail.com9829357194

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026