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Administration of Bolus (single dose of drug given over a short period) Dexmedetomedine Versus Esmolol For Stress Attenuation During Laryngoscopy And Endotracheal Intubation:Randomised,Comprative And Double Blind Study

Administration of Bolus Dexmedetomedin Versus Esmolol For Stress Attenuation During Laryngoscopy And Endotracheal Intubation:Randomised,Comprative And Double Blind Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/01/030828
Enrollment
60
Registered
2021-01-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: nil: nil Control Intervention1: nil: nil

Sponsors

Indira Gandhi Institute Of Medical Sciences Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient of American Society Of Anaesthesiologist Grade 1 and 2 having Mallampati grade 1 and 2

Exclusion criteria

Exclusion criteria: Patient with Pregnancy , Morbid obesity, Full stomach.

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of bolus administration of intravenous dexmedetomedine with intravenous esmolol in attenuating the cardiovascular stress response accompanying laryngoscopy and endotracheal intubation.Timepoint: Immediately after induction and intubation, the stress response ( reflected by blood pressure, heart rate etc) will be recorded without any delay.—

Secondary

MeasureTime frame
to look for any significant adverse effect of these drugs.Timepoint: immediately after induction and intubation,without any delay, adverse effect of these drugs will be recorded, if any.—

Countries

India

Contacts

Public ContactVinod Kumar Verma

IGIMS, Patna

ananturocks07@rediffmail.com7903752618

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026