Dexmeditomedine versus Morphine for sedation in preterm babies

Dexmeditomedine vs Morphine Infusion for pain relief in mechanically ventilated preterm neonates: A Randomized Control Study

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/01/030771

Enrollment

Registered

2021-01-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P073- Preterm [premature] newborn [other]

Interventions

Intervention1: Dexmeditomedine: Babies in this group will receive injection Dexmeditomedine stat dose 0.5 micrograms/kg followed by infusion of 0.2 mics/kg/hr. All babies are assessed for pain and sed

Eligibility

Inclusion criteria

Inclusion criteria: Preterm neonates between 28 and 36 weeks of gestation needing mechanical ventilation

Exclusion criteria

Exclusion criteria: Term babies Babies with congenital anomalies

Design outcomes

Primary

Measure	Time frame
Time to achieve pain relief in the first 24 hours of commencing mechanical ventilation and hemodynamic stability during the study period.Timepoint: Pain to be assessed once in every 2 hours	—

Secondary

Measure	Time frame
hemodynamic instability in terms of bradycardia or hypotension needing inotropes.Timepoint: Within 24 hours	—

Countries

India

Contacts

Public ContactDr Deepti Thandaveshwara

JSS Medical College

deeptiadarsh@gmail.com09845023309

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026