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Comparison of 2mg and 5mg Nalbuphine as an adjuvant to Ropivacaine in spinal anaesthesia for patients Undergoing elective lower limb surgeries

Comparative Efficacy of 2mg and 5mg Intrathecal Nalbuphine as an Adjuvant to Ropivacaine in Elective Lower Limb Surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030645
Enrollment
90
Registered
2021-01-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: 8- Other Procedures

Interventions

Intervention1: 2mg of Intrathecal Nalbuphine as an adjuvant to Ropivacaine: Group A will receive 2mg of Nalbuphine made up to 0.5ml volume with normal saline +isobaric Ropivacaine 0.75% 3ml (Total vol

Sponsors

Veer Surendra Sai institute of medical science and research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1&2 Planned for elective lower limb surgeries

Exclusion criteria

Exclusion criteria: Pregnant patients Patients with co morbidities like hypertension and diabetes Patient having contraindications to SAB Weight more than 100kg and less than 30kg Patients receiving CNS depressant drugs Patient having cardiac renal respiratory disease H/o adverse reactions to Ropivacaine and Nalbuphine

Design outcomes

Primary

MeasureTime frame
Intrathecal Nalbuphine can be used as a good adjuvant to subarachnoid block as it can prolong both sensory and motor blockade with minimal side effects Low dose Nalbuphine (2mg) will be producing equal motor and prolonged analgesia as compared to 5mg of Nalbuphine with lesser side effectsTimepoint: 4-6hours

Secondary

MeasureTime frame
Adverse effectsTimepoint: Within 10 hour after spinal anaesthesia

Countries

India

Contacts

Public ContactDr Dulal Kisun Soren

Department of Anaesthesiology and critical care,VSSIMSAR,BURLA

dulalsoren@gmail.com9437254980

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026