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Effect of two chewing gum in caries active children

Efficacy of xylitol and IgY impregnated chewing gum on streptococcus mutans in caries active children - A PCR Study

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030633
Enrollment
30
Registered
2021-01-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Efficacy of xylitol chewing gum: Children will be ask to chew one pellet of xylitol chewing gum ,two times a day after a meal for 30 days Baseline sample collected before intervention a

Sponsors

Dr Gayathri G
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)children aged with 5-8 years 2)children having a DMFT/dmft index between 3-6years 3)children who have not received probiotic/xylitol/IgY therapy earlier 4)children with no systemic diseases

Exclusion criteria

Exclusion criteria: 1)children with history of intake for preceding one month 2)children with history of topical fluoride therapy for preceding one month 3)children with congenital abnormalities,mental disorder and debilitating diseases 4)caries free children 5)children with acute foci of infection in the oral cavity 6)children with history of corticosteroid therapy for preceding 4 week

Design outcomes

Primary

MeasureTime frame
Impregnated chewing gums reduce streptococcus mutans level in plaque and saliva to prevent dental cariesTimepoint: baseline (fixed point of reference that is used for comparison purposes)sample before intervention follow up sample after 30 days

Secondary

MeasureTime frame
Efficacy of xylitol and IgY impregnated chewing gums on streptococcus mutans in caries active childrenTimepoint: Baseline sample before intervention and follow up sample after 30 days

Countries

India

Contacts

Public ContactDr Gayathri G

Rajarajeswari dental college and hospital

jaya.vrushabh@gmail.com9880038038

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026