Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
None listed
Sponsors
Dr Anoop Shah
Eligibility
Inclusion criteria
Inclusion criteria: COVID-19 positive patients 1-COVID-19 positive 2-Ideally 2 weeks withina positive test (but can be extended to 4 weeks) 3-Symptoms suggestive of an acute respiratory viral illness Positive controls 1-COVID-19 negative (PCR andserology) 2-Symptoms suggestive of an acute respiratory viral illness Negative controls 1-COVID-19 negative (PCR andserology) 2-Absence of symptoms of acute respiratory viral illness
Exclusion criteria
Exclusion criteria: 1-Prior diagnosis of myocardial infarction 2-Prior diagnosis of a non-ischaemic cardiomyopathy 3-Patients requiring invasive or non-invasive ventilation 4-Previous coronary revascularisation or cardiac surgery 5-Patient inability to undergo CT or CMR scanning, due to severe renal failure (estimated glomerular filtration rate 6-Pregnancy or breast feeding 7-Inability to give informed consent 8-Contraindication to imaging, example metal fragments in the eye
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A. Identify the proportion of patients with biochemical evidence of myocardial injury or strain i.Presence of elevated cardiac troponin or NTproBNP concentrations B. Identify the presence of atherosclerotic disease CTCA i.Presence of obstructive coronary artery disease on CTCA 70% C.Identify myocardial disease D.Identify vascular inflammation PET scan E. Describe and quantify degree of pulmonary fibrosis F. Describe the change across cases and positive controlsTimepoint: 6 Months | — |
Secondary
| Measure | Time frame |
|---|---|
| B. Identify the presence of atherosclerotic disease CTCA i.Presence of obstructive coronary artery disease on CTCA 70% C.Identify myocardial disease D.Identify vascular inflammation PET scan E. Describe and quantify degree of pulmonary fibrosis F. Describe the change across cases and positive controlsTimepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr C Narasimhan
AIG Hospital
Outcome results
None listed