Health Condition 1: - Health Condition 2: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention1: Cardamom extract: Dose:200 mg
Dosage form: Capsule
Duration: Day 0 to Day 7
Frequency : 3 times daily orally after meal
Control Intervention1: NIL
standard of care recommended by GOVt
Sponsors
Zum Heilen Diagnostic Therapeutics ZH DT
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects aged 18-65 years of age and of either sex 2. Subjects who are willing to give consent to the study 3. COVID-19 positive clinical symptoms and (subsequently) confirmed by the current recommended confirmatory test (RT-PCR). 4. Mild to Moderate disease (NEWS score Less than/equal to 8) 5. Can take oral medicines 6. Subject willing to abide by and comply with the study protocol.
Exclusion criteria
Exclusion criteria: 1. Age less than 18 years and more than 65 years 2. Pregnancy and lactation 3. Severe or complicated course of COVID-19 disease 4. Presence of acute hypoxic respiratory failure/ need for Intensive care unit (ICU) stay/ Patients who need mechanical ventilation. 5. Any uncontrolled systemic disease, infection 6. Those with serious Cardiovascular, Cerebrovascular, Respiratory, Liver or Renal disease or any other disorder. 7. Other conditions, which in the opinion of the investigators makes the patient unsuitable for enrolment or could interfere in adherence to of the study protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â?¢ Change in Chest CT severity score (CO-RADS) from baseline to day 7 â?¢ Change in Viral load from baseline to day 7 â?¢ Change in immune markers (IL-6, LDH, TNF, TLC, ALC, FERRITIN, CRP and D-DIMER) from baseline to day 7 Timepoint: Day 0 and Day 7 | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ Change in National Early Warning Score (NEWS) from baseline to day 7 â?¢ Change in clinical symptoms on 5 point ordinal scale from baseline to day 7 â?¢ Number of patients tested COVID 19 RT-PCR negative at day 7 â?¢ Number of patients requiring intensive care treatment (ICU) at day 7 â?¢ Number of patients requiring Ventilator support at day 7 Timepoint: Day 0 and Day 7 | — |
Countries
India
Contacts
Public ContactDr Prashanth
Zum Heilen Diagnostic and Therapeutics
Outcome results
None listed