Health Condition 1: C40- Malignant neoplasm of bone and articular cartilage of limbs Health Condition 2: C15-C26- Malignant neoplasms of digestive organs
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
Tata Memorial Hospital
Not Any
Eligibility
Inclusion criteria
Inclusion criteria: 1) Adult patients ( > 18 years) with a normal preoperative platelet count and coagulation profile. 2)Elective major surgery (Esophagectomy, Gastrectomy, Whipples, Hemipelvectomy, Sacrectomy, Cytoreductive surgery and HIPEC) with major blood loss/massive transfusion 3)ASA grade I, II, III
Exclusion criteria
Exclusion criteria: 1)Preoperative deranged platelet count/coagulation profile 2)Patient on anticoagulant therapy 3)Patient with bleeding disorders 4)Emergency surgeries 5)Paediatric population 6)Hepatectomy (as these patients are being enrolled in another trial) 7)Postoperative epidural catheter insertion
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| The average perioperative blood loss in these surgeriesTimepoint: Post operative day1, day 2, day3 and 1 month after removal of Epidural catheter;Epidural catheter duration (days in situ)Timepoint: 1 month after removal of Epidural catheter;Percentage of patients in whom a TEG (viscoelastic testing) was done prior to epidural catheter removalTimepoint: Post operative day1, day 2, day3 and 1 month after removal of Epidural catheter;The percentage of patients requiring Vitamin K and /or blood products (FFP and/or platelets) to correct the derangement prior to catheter removalTimepoint: Post operative day 1, day 2, day 3;The percentage of such patients developing complications related to epidural catheter removal i.e, catheter related infection, epidural hematomaTimepoint: Post operative day1, day 2, day3 and 1 month after removal of Epidural catheter | — |
Primary
| Measure | Time frame |
|---|---|
| To identify the percentage of patients with deranged coagulation profile in the postoperative period potentially delaying/ interfering with epidural catheter removalTimepoint: Post operative day1, day 2, day3 and 1 month after removal of Epidural catheter | — |
Countries
India
Contacts
Public ContactDr Keerthana Kalai
Tata Memorial Hospital
Outcome results
None listed