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Comparison of two blood products in healing of extraction sockets - A split mouth randomized clinical trial

Comparison of Leukocyte and Platelet Rich Fibrin and Advanced Platelet Rich Fibrin in healing of extraction sockets â?? A split mouth randomized clinical trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030564
Enrollment
20
Registered
2021-01-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: leukocyte and platelet rich fibrin: a blood product produced by centrifuging patients own blood at 3000 rpm for 10 min Control Intervention1: advanced platelet rich fibrin: a modified v

Sponsors

Sanchit Mahajan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subject requiring surgical removal of bilateral impacted mandibular third molars. 2.Subject requiring surgical removal of Soft tissue impacted mandibular third molar 3.Subjects who are in good physical health with no clinically significant and relevant 4.No medical history. 5.Subject who understood and are willing to follow with all study procedure.

Exclusion criteria

Exclusion criteria: 1.Subject requiring surgical removal of unilateral impacted mandibular third molars 2.Subject unable or unwilling to sign the informed consent form. 3.Immunocompromised individuals including those with severe debilitating diseases. 4.Pregnant, lactating or female subjects taking oral contraceptive were not included. 5.Patients who are smokers will be excluded from the study

Design outcomes

Primary

MeasureTime frame
comparison of bone density will be done on both sides using a cone beam computed tomographyTimepoint: at 6 months

Secondary

MeasureTime frame
post operative pain and swelling on either side will be measuredTimepoint: pain and swelling will be measured on 1st 3rd and 7th post op day

Countries

India

Contacts

Public ContactSanchit Mahajan

Manipal College of Dental Sciences, Mangalore

premalatha.shetty@manipal.edu9448509022

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026