FindTrial
Sign In

Effect of intraoperative dexamethasone on blood lactate level in patients undergoing craniotomy: A randomized control trial

Effect of intraoperative dexamethasone on arterial blood lactate level in patients undergoing craniotomy: A prospective, double-blinded, randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030550
Enrollment
66
Registered
2021-01-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: DEXAMETHASONE: dexamethasone 8 mg ( 2 ml of the drug ) given intravenously after induction of anesthesia Control Intervention1: PLACEBO: NS 0.9 % equal volume ( 2 ml ) given intravenou

Sponsors

AIIMS BHUBANESWAR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for craniotomy surgeries

Exclusion criteria

Exclusion criteria: Refusal to give consent. Patients with raised lactate as in ï?§ Hemodynamically unstable ï?§ Liver / renal failure

Design outcomes

Primary

MeasureTime frame
Change in blood lactate level [â?? lactate ](i.e.difference between preoperative and early postoperative values )Timepoint: 1 ) Preoperative i.e. after induction , 2 ) Early postoperative i.e. after dura closure .—

Secondary

MeasureTime frame
Blood lactate level 24 hr post-operatively Blood sugar level at end of surgery and 24 hr post-op Length of hospital stay Timepoint: 24 hrs postoperatively—

Countries

India

Contacts

Public ContactRUSIKESH SATAPATHY

AIIMS BHUBANESWAR

tripathyswagata@gmail.com8763400534

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026