Effect Of Palonosetron In The Prevention Of Spinal Anaesthesia Induced fall in Blood pressure and Heart rate.

Effect Of Palonosetron In The Prevention Of Spinal Anaesthesia Induced Hypotension and Bradycardia.

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/01/030524

Enrollment

150

Registered

2021-01-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R688- Other general symptoms and signs

Interventions

Intervention1: Palonosetron 0.075mg: Giving Palonosetron 0.075mg in 4ml Normal Saline 10 mins prior to surgery(study group) Control Intervention1: Palonsetron 0.075mg in 4ml normal saline.: Comparing

Eligibility

Inclusion criteria

Inclusion criteria: Patients Of ASA Grade I & II Posted For Surgeries Under Spinal Anaesthesia

Exclusion criteria

Exclusion criteria: 1. Hypertension on medication 2. Diabetic neuropathy 3. Pregnancy 4. BMI > 30 5. Patients receiving selective serotonin reuptake inhibitors or migraine medication 6. Patient refusal 7. Hypersensitivity to palonosetron.

Design outcomes

Primary

Measure	Time frame
Measuring systolic blood pressure, Diastolic blood pressure, and Mean blood pressure at 3 min interval. Measuring Heart rate continuouslyTimepoint: Measuring systolic blood pressure, Diastolic blood pressure, and Mean blood pressure at 3 min interval. Measuring Heart rate continuously	—

Secondary

Measure	Time frame
To assess the need of vasopressorsTimepoint: every 3 minute interval	—

Countries

India

Contacts

Public ContactDR D J Pradeep

KALINGA INSTITUTE OF MEDICAL SCIENCES

drakparida@gmail.com6281345706

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026