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Comparison of different root canal microorganisms and to search for an effective treatment

Comparative clinical characterization of microflora between primary and secondary endodontic infections with subsequent use of photodynamic therapy.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030509
Enrollment
132
Registered
2021-01-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K049- Other and unspecified diseases ofpulp and periapical tissues Health Condition 2: K049- Other and unspecified diseases ofpulp and periapical tissues Health Condition 3: R688- Other general symptoms and signs

Interventions

Intervention1: Photodynamic Therapy: Efficacy of Photodynamic Therapy on Secondary Root canal infections (retreatment cases) duration of 5 minutes to 18 minutes of intervention Control Intervention1:

Sponsors

MAHANTESH YELI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: GROUP 1 Inclusion criteria Age- 18- 80 years Single and multi-rooted non vital teeth with radiographic periapical radiolucency GROUP 2 Inclusion criteria Age- 18- 80 years Single and multi-rooted teeth Teeth which are root canal treated >2 years previously Radiographically Periapical radiolucency seen Obturation material reached within 4 mm of the radiographic apex.

Exclusion criteria

Exclusion criteria: Group 1 Exclusion criteria Patients who have received antibiotics and corticosteroids for the same Systemic diseases Pregnant and lactating women More than 5mm loss of periodontal attachment Tobacco chewers and smokers Group 2 Exclusion criteria Patients who have received antibiotics and corticosteroids for the same Systemic diseases Pregnant and lactating women More than 5mm loss of periodontal attachment Tobacco chewers and smokers.

Design outcomes

Primary

MeasureTime frame
Identification and culture of commonly prevalent strains in primary and secondary infections of root canal. And subjecting select microorganisms for molecular methods.Timepoint: Sample collection at baseline and 1 day—

Secondary

MeasureTime frame
Evaluation of the efficacy of photodynamic therapy in the disinfection of root canals in teeth requiring endodontic re-treatment. Comparison of LED light and diode laser for photodynamic disinfection of root canals in teeth requiring endodontic re-treatment. Timepoint: Pre intervention assessment and post intervention assessment of secondary root canal infections. Samples are collected at baseline and 1 day.—

Countries

India

Contacts

Public ContactBALARAM NAIK

SDM COLLEGE OF DENTAL SCIENCES AND HOSPITAL

drbalaramnaik2@gmail.com9448867636

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026