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To see the postoperative analgesic effect of transdermal buprenorphine patch applied preoperatively in major abdominal surgeries

Efficacy of preoperative buprenorphine patch(12 hrs versus 24 hrs) on postoperative analgesia following major abdominal surgeries.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030441
Enrollment
66
Registered
2021-01-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified

Interventions

Intervention1: Comparing post operative analgesic effect of transdermal patch applied 12 hrs versus 24 hrs preoperatively.: buprenorphine patch(10mg) will be applied 12 hours pre-operatively. Interven

Sponsors

Dr Aanal Vyas
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a total of 66 patients belonging to ASA grade 1-3,aged between 18 to 70 years, of either gender posted for major abdominal surgery under general anaesthesia with incision extending upto epigastrium were included.

Exclusion criteria

Exclusion criteria: History of allergy to study drug • History of excessive alcohol intake/ alcohol dependence syndrome • Pre existing cardiac diseases, uncontrolled hypertension, diabetes mellitus • Severe asthma, chronic obstructive pulmonary diseases • Hepatic and renal dysfunction • A chronic pain syndrome • Regular use of opiates, pain medications • Pregnant or lactating women

Design outcomes

Primary

MeasureTime frame
To evaluate post operative analgesic effect of buprenorphine patch applied preoperatively before 12 hr and 24 hours on the basis of VAS score, time of first rescue analgesia, and total number of doses.Timepoint: From patch application till 72 hours postoperatively.—

Secondary

MeasureTime frame
Haemodynamic variables â?¢ Sedation score â?¢ Quality of recovery score â?¢ Adverse effect of study drugTimepoint: Preoperatively before 12/24 hrs, intraoperatively, and postoperatively till 72 hours.—

Countries

India

Contacts

Public ContactDr Seema partani

Geetanjali medical college

partaniseema@yahoo.in9414162150

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026