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Role of oral carbohydrate for prevention of postoperative blood glucose increase in patients receiving dexamethasone for PONV prophylaxis

Comparison of postoperative blood glucose in patients receiving dexamethasone for PONV prophylaxis with or without Preoperative Oral Carbohydrate: A randomised controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030376
Enrollment
40
Registered
2021-01-11
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Preoperative Oral carbohydrate: Preoperative oral carbohydrate will be given and postoperative blood glucose will be recorded Control Intervention1: No pre-operative carbohydrate will b

Sponsors

University College of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I/II 18-65 years Undergoing elective surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: Anti-emetic drugs or steroid administration within 24 hr before anaesthesia K/c/o diabetes mellitus, pheochromocytoma, carcinoid tumour, gastro-oesophageal reflux, gastric outlet/ intestinal obstruction, PONV, motion sickness, migraine H/o pancreatitis, alcoholism, jaundice or liver disorders Obesity (BMI >30 kg/m2) Pregnancy or lactation Emergency surgery Patients on continuous steroid therapy for >5 days in the last one year.

Design outcomes

Primary

MeasureTime frame
Blood glucoseTimepoint: Just before induction of general anaesthesia (S0), immediate postoperatively (S1), 6 hr after dexamethasone (S2), 24 hr after Sx (S3), 48 hr after Sx (S4), 72 hr after Sx (S5).—

Secondary

MeasureTime frame
anxiety, hunger and thirst Timepoint: just before GA and immediately postoperatively;Postoperative Nausea/vomitingTimepoint: 0, 30, 60, 90 and 120 min and 24 h postoperatively—

Countries

India

Contacts

Public ContactDeepasri Malakar

University College of Medical Sciences, Delhi

rashmichabra@yahoo.com9911317334

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026