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CMV reactivation in ICU patients

Cytomegalovirus reactivation in critically ill immunocompetent patients with septic shock

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/01/030371
Enrollment
125
Registered
2021-01-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B108- Other human herpesvirus infection

Interventions

None listed

Sponsors

Sanjay Gandhi Post Graduate Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult ICU patients (age >= 18 years) who had septic shock will be considering for inclusion in this study.

Exclusion criteria

Exclusion criteria: 1.Consent not given. 2.Expected survival 3.Use of antiviral agent cidofovir, foscarnet, ganciclovir, valgancyclovir [HSV treatment doses of acyclovir, valacyclovir, or famciclovir permitted]) within the last 7 days. 4.Known or suspected underlying immune deficiency [history of solid organ or stem cell transplantation, infection with the human immunodeficiency virus, hematological malignancy, use of immunosuppressive medication (more than 0.1 mg prednisone per kilo for more than 3 months, more than 75 mg prednisone per day for more than 1 week, or equivalent), chemotherapy/radiotherapy in the year before ICU admission, and any known humoral or cellular immune deficiency]. 5.Pregnancy.

Design outcomes

Primary

MeasureTime frame
1. To study the prevalence of CMV reactivation in critically ill septic shock patient.Timepoint: 2 years

Secondary

MeasureTime frame
Determine the association of CMV reactivation on patient outcomes, length of ICU stay as well as on duration of mechanical ventilation on non-immunosuppressed patients with septic shock.Timepoint: 2 years

Countries

India

Contacts

Public ContactAtul Garg

Sanjay Gandhi Post Graduate Institute of Medical Sciences

atulgargsgpgi@gmail.com08953552392

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026