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To compare the effect of using conventional method of assessing blood loss versus using continuous non invasive Haemoglobin monitoring method on blood transfusion during decompression surgery for acute brain injury patients

"Impact of Continuous non-invasive Haemoglobin monitoring on red blood cell transfusion during decompressive craniotomy for acute brain injury: A randomized control study".

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030347
Enrollment
80
Registered
2021-01-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S069- Unspecified intracranial injury

Interventions

Intervention1: Packed Red blood cell transfusion: Assessment of Haemoglobin drop to 10gm% using two different methods. Conventional method of assessing looking at the intraoperative blood loss and the

Sponsors

Dr Geetha L
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-65 years scheduled for decompressive craniotomy 2 Acute brain injury defined as intracranial injury presented within 48 hrs of insult (traumatic and non-traumatic) and diagnosed by imaging of the brain (CT/MRI) which require decompression surgery. 3 ASA 1-3

Exclusion criteria

Exclusion criteria: 1 Pre-existing anaemia with Hb concentration 2. Patients with coagulopathy with international normalised ratio (INR) >1.5. 3. Patients with history of severe cardiac, pulmonary, liver or renal disease, or obesity (body mass index >30) and pregnancy will be excluded from this study. • Patients who are hemodynamically unstable. • Head injuries associated with other organ/ tissue trauma • Patients / relatives refusing to give consent.

Design outcomes

Primary

MeasureTime frame
1. Difference in the number of Red blood cell units transfused in acute head injury patients during decompressive craniotomy guided by SpHb (continuous non-invasive Hb monitoring) vs conventional estimated blood loss method.Timepoint: Total Red blood cells transfused through out the intraoperative period.—

Secondary

MeasureTime frame
1. Incidence of post-operative infections 2. Length of stay in ICU 3. Difference in the mortality 4. Neurological outcome using E-GOS (Extended Glasgow outcome scale) Timepoint: 1. Incidence of post operative infections during first week of ICU stay 2.Total number of ICU days immediately in the immediate post operative period 3.Difference in the 30 post operative day mortality 4.E-GOS score at 90 days of post discharge from hospital—

Countries

India

Contacts

Public ContactDr Geetha L

Dept of Anaesthesia Neuroanaesthesia Division M S Ramaiah Medical College and Hospitals

geetha4kiran@yahoo.in9611897899

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026