Health Condition 1: - Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 2. BMI: 18.5 â?? 29.99 kg/m2 e GFR > 60 ml / minute / 1.73m2 Non-cardiac, non vascular major plus surgeries (NICE grade 4) ASA I to III
Exclusion criteria
Exclusion criteria: ASA IV and above Emergency surgery Jail inmates, HIV patients, Pregnant women Patient receiving contrasts during surgery Intraop MAP Hypotensive anaesthesia Known case of nephropathy, chronic kidney disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a.To quantify the problem of AKI in major plus non-cardiac, non-vascular surgeries b. To assess the ability of NGAL based biomarker assay in detecting AKI early c.To assess the clinical implication of NGAL based diagnosis on morbidity and mortality (if any) Timepoint: Post op Hb, serum creatinine and blood urea will be measured at 4 h post surgery and daily thereafter up to postoperative day 3. â?¢ Blood sample for NGAL levels will be taken preoperatively and at 4h and 24 h post surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| c. To assess the clinical implication of NGAL based diagnosis on morbidity and mortalityTimepoint: Post op Hb, serum creatinine and blood urea will be measured at 4 h post surgery and daily thereafter up to postoperative day 3. â?¢ Blood sample for NGAL levels will be taken preoperatively and at 4h and 24 h post surgery | — |
Countries
India
Contacts
AIIMS, Raipur