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Incidence of Kidney Injury after major surgeries: assessment with new investigation NGAL and its role in early diagnosis

Incidence of Acute Kidney Injury after non-cardiac major plus surgeries: a prospective assessment with NGAL and its clinical implications

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/01/030345
Enrollment
60
Registered
2021-01-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical

Interventions

None listed

Sponsors

AIIMS Raipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 2. BMI: 18.5 â?? 29.99 kg/m2 e GFR > 60 ml / minute / 1.73m2 Non-cardiac, non vascular major plus surgeries (NICE grade 4) ASA I to III

Exclusion criteria

Exclusion criteria: ASA IV and above Emergency surgery Jail inmates, HIV patients, Pregnant women Patient receiving contrasts during surgery Intraop MAP Hypotensive anaesthesia Known case of nephropathy, chronic kidney disease

Design outcomes

Primary

MeasureTime frame
a.To quantify the problem of AKI in major plus non-cardiac, non-vascular surgeries b. To assess the ability of NGAL based biomarker assay in detecting AKI early c.To assess the clinical implication of NGAL based diagnosis on morbidity and mortality (if any) Timepoint: Post op Hb, serum creatinine and blood urea will be measured at 4 h post surgery and daily thereafter up to postoperative day 3. â?¢ Blood sample for NGAL levels will be taken preoperatively and at 4h and 24 h post surgery

Secondary

MeasureTime frame
c. To assess the clinical implication of NGAL based diagnosis on morbidity and mortalityTimepoint: Post op Hb, serum creatinine and blood urea will be measured at 4 h post surgery and daily thereafter up to postoperative day 3. â?¢ Blood sample for NGAL levels will be taken preoperatively and at 4h and 24 h post surgery

Countries

India

Contacts

Public ContactMonica Khetarpal

AIIMS, Raipur

monicakhetrapal@yahoo.com8518881714

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026