A clinical trial to study whether the patients own bone marrow stem cells can improve or prevent the nerve damage following polio infection

Role of autologous bone marrow mononuclear stem cells in children with neurological deficits due to polio infection - STEMPOL

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/01/030327

Enrollment

Registered

2021-01-07

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 1. Bone marrow mononuclear cells 2.Granulocyte colony stimulating factor : 1. Bone marrow mononuclear cells Caudal Epidural Space Dose 1-100 million cells one time injection 2. Granul

Eligibility

Inclusion criteria

Inclusion criteria: Children between 2 years and 25 years with neurological deficit in the form of defective limb movement and diagnosed as Acute flaccid paralysis due to poliomyelitis by a pediatrician. The patient or his/her guardian giving well informed consent to be included in the blind study

Exclusion criteria

Exclusion criteria: Patients less than 2 years of age or more than 18 years of age. Patients with severe infection with involvement of the respiratory muscles or a chronic source of infection like tonsillitis, UTI. Patients not willing for the study or wanting to drop out later.

Design outcomes

Primary

Measure	Time frame
Electro myography resultsTimepoint: 6 months	—

Secondary

Measure	Time frame
Muscle charting and Physical handicapTimepoint: 1,3,6,12,24,36,60 months	—

Countries

India

Contacts

Public ContactDr Shilpa Sharma

All India Institute of Medical Sciences

drshilpas@gmail.com9810863996

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026