Health Condition 1: I958- Other hypotension
Conditions
Interventions
Intervention1: Restricted volume group: 10 ml/kg group: In this group, children will be managed as per American College of Critical Care Medicine guidelines (2017) for management of septic shock. The
Sponsors
All India Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Children 2 month to 17 years of age with features of septic shock – defined as children who have a suspected infection manifested by hypothermia or hyperthermia and have at least two clinical signs of decreased perfusion with or without hypotension
Exclusion criteria
Exclusion criteria: Children receiving boluses before enrolment Children with chronic kidney disease. Children with fulminant myocarditis Children with dengue shock syndrome Children with malaria Children with severe anemia (Hb • Severe acute malnutrition (wt/ht • Post-arrest shock and cardiac dysfunction • Moribund patients in who anticipated survival is
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Shock resolution at 6 hoursTimepoint: At 6 hours of resuscitation | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion having fluid overload in first 24 hours , 48 hours and 72 hoursTimepoint: Measured at 24 hours, 48 hours and 72 hours of resuscitation;Vasoactive inotrope scoreTimepoint: Measured at 24 48 and 72 hours;Ventilator free daysTimepoint: Measured at day 28 since enrollment;ICU free daysTimepoint: Measured at day 28 of enrollment;Organ dysfunction using pediatric Sequential Organ Failure Assessment(pSOFA)scoreTimepoint: Measured at 24, 48 and 72 hours | — |
Countries
India
Contacts
Public ContactJhuma Sankar
AIIMS Delhi
Outcome results
None listed