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Dexamethasone versus dexmedetomidine for prevention of shivering after spinal anaesthesia in Caesarean Section

Prophylactic intravenous dexamethasone versus dexmedetomidine for post spinal shivering during LSCS : A prospective randomized, double-blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030303
Enrollment
225
Registered
2021-01-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Dexamethasone: Dexamethasone is a synthetic glucocorticoid which has anti-inflammatory and analgesic property. In addition to this, it has got properties to prevent postoperative shiver

Sponsors

Pt JNM Medical college Dr BRAM Hospital Raipur CG
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Physical status â??Ð?Ð? Singleton term pregnancy Caesarean delivery Weight 40-100kg Height 135-180cm

Exclusion criteria

Exclusion criteria: Cardiovascular or cerebrovascular disease Renal impairment Allergy to dexamethasone dexmedetomidine or bupivacaine Eclampsia Severe liver disorders Novel corona virus positive Known history of substance abuse or alcohol abuse Initial core temperature of >38.0°C or Blood transfusion during surgery Hypo or Hyperthyroidism Convulsion or psychiatric disorders

Design outcomes

Secondary

MeasureTime frame
Shivering score Sedation score Incidence of hypotension Incidence of bradycardia Incidence of desaturation Incidence of nausea and vomiting Incidence of Pruritus Side effects / complications Apgar scoreTimepoint: 0 to 90 minutes

Primary

MeasureTime frame
Primary- Shivering score Secondary- Sedation score Incidence of hypotension Incidence of bradycardia Incidence of desaturation Incidence of nausea and vomiting Incidence of Pruritus Apgar score Timepoint: Baseline, 0 to 20 minutes (at 2 minutes interval ) and 20 to till end of surgery (at 5 minutes interval)

Countries

India

Contacts

Public ContactDr Pratibha Jain Shah

Pt.JNM Medical college, Raipur (CG)

prati_jain@rediffmail.com9827276620

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026