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Effect of Adding Epinephrine to Bupivacaine and Dexmedetomidine in Ephinephrine Anaesthesia for Lower Limb Surgeries

The Effect of Adding Epinephrine To Combination of 0.5% Bupivacaine and Dexmedetomidine in Epidural anaesthesia for Lower Limb Surgeries - A Prospective, Double Blinded Randomized Control Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030282
Enrollment
50
Registered
2021-01-06
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S90-S99- Injuries to the ankle and foot Health Condition 2: S70-S79- Injuries to the hip and thigh Health Condition 3: S80-S89- Injuries to the knee and lower leg Health Condition 4: O- Medical and Surgical Health Condition 5: O- Medical and Surgical Health Condition 6: S929- Unspecified fracture of foot and toe Health Condition 7: S999- Unspecified injury of ankle and foot Health Condition 8: S999- Unspecified injury of ankle and foot Health Condition 9: S899- Unspecified in

Interventions

Intervention1: Epidural anaesthesia at the L2-4 level in sitting position: Patients were administered epidural block with 18 gauge Touhy needle at the L2-4 level in sitting position, catheter was sec

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 & 2 Lower limb surgery of probable duration of 2hrs.

Exclusion criteria

Exclusion criteria: Patients refusal Contradiction to regional anaesthesia Coagulopathy History of significant coexisting diseases like ischemic heart disease, hypertension, impaired renal functions, rheumatoid arthritis, and severe liver disease Pregnant patients Chronic alcoholics and malnourished patients Atrioventricular block, incomplete or partial heart blocks or intake of beta-blockers

Design outcomes

Primary

MeasureTime frame
Duration of analgesiaTimepoint: After 2 hours every 15 minutes

Secondary

MeasureTime frame
Duration of sensory block & motor blockTimepoint: After 2 hours every 15 minutes

Countries

India

Contacts

Public ContactDR SHEKHAR ANAND

TRAUMA CENTER BHU

drsandeepscb@gmail.com8960919866

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026