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A randomized control trial on vasovagal reaction prevention strategies in whole blood donors

Vasovagal reaction prevention strategies in whole blood donors: A quadri-armed randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030249
Enrollment
4000
Registered
2021-01-05
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: pre-donation water ingestion: Donors will be allocated into four arms of the study according to randomization method applied by nQuery advance software using mixed block randomization.
water ingestion group will be asked to drink with 250 mL of plain water within 30 min before whole blood donation. Intervention2: pre-donation applied muscle tension: donors allocated to this group wi

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Donor eligible according to the Departmental SOP and recent DCA amendment 2. Donors of age group �18 to 65 years 3. Both male and female donors 4. All first-time blood donors and 5. All repeat blood donors

Exclusion criteria

Exclusion criteria: 1. Repeat donors with more than 3 previous donations within 2 years

Design outcomes

Primary

MeasureTime frame
Frequency of VVR in intervention group compared to the non-intervention group.Timepoint: Outcomes will be assessed immediately post donation and after one week.—

Secondary

MeasureTime frame
Effectiveness of VVR prevention strategiesTimepoint: at the end of the study—

Countries

India

Contacts

Public ContactDr Radheshyam Meher

All India Institute of Medical Sciences, New Delhi

drgpatidar@gmail.com9781089405

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026