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Comparison of the effects of normal saline versus plasmalyte on acid base balance during living donor kidney transplantation using pulse pressure variation

Comparison of the effects of normal saline versus plasmalyte on acid base balance during living donor kidney transplantation using fluid therapy guided by pulse pressure variation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/01/030227
Enrollment
58
Registered
2021-01-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease

Interventions

Intervention1: Plasmalyte fluid: Giving intravenous route, bolus of 250ml and maintenance dose of 4ml/kg/hr fluid given throughout the surgery and calculating Strong ion difference at end of surgery

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients with ESRD Scheduled for renal transplant surgery

Exclusion criteria

Exclusion criteria: Active coronary disease Congestive heart failure Atrial fibrillation or flutter Valvular heart disease Significant pulmonary insufficiency Cadaveric renal transplant

Design outcomes

Primary

MeasureTime frame
To determine inter group difference in strong ion difference at end of surgeryTimepoint: At end of surgery—

Secondary

MeasureTime frame
Blood urea nitrogen and serum creatinineTimepoint: On day one post operative;Graft failureTimepoint: Within seven days;Serum potassium chloride sodium lactateTimepoint: On day one post operative;Total fluid administered at end of surgeryTimepoint: At end of surgery;Urine outputTimepoint: 24hrs—

Countries

India

Contacts

Public ContactSachin kumar

Postgraduate institute of medical education and research Chandigarh

Kamal.kajal@gmail.com7087009545

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026