Evaluation of 2% amitriptyline gel for topical anesthesia

Design development and evaluation of 2% amitriptyline gel for topical anesthesia

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/01/030175

Enrollment

Registered

2021-01-01

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Amitriptyline gel: Amitriptyline gel as local anesthetic agent topical route of administration one application before dental procedure in the oral mucosa Control Intervention1: Lignocai

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients requiring bilateral Local anesthesia for any invasive dental procedure. 2. Without prior exposure to local anesthesia

Exclusion criteria

Exclusion criteria: 1. Any drug allergy or systemic disease 2. Presence of sinus tract at the site of local anesthesia 3. Patients with lack of orientation or mental disabilities

Design outcomes

Primary

Measure	Time frame
NILTimepoint: NIL	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Shoba Fernandes

Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University

vshobaf@gmail.com7567622346

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026