Health Condition 1: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified
Conditions
Interventions
Intervention1: Dexmedetomidine, bupivacaine,levobupivacaine and ropivacaine: Our study is a 4 arm study, the intervension agents in our study are dexmedetomidine+ bupivacaine 0.5%,
dexmedetomidine +
Sponsors
Dr Ramana Reddy MV
Eligibility
Inclusion criteria
Inclusion criteria: Eighty adult patients of age 18 and 80 yrs of either sex with weight betweeen 50 and 80kg and who were of American Society of Anaesthesiologists (ASA) grade I and II, attending our medical college hospital for surgeries of upper limb between the period 01-1-2021 and 31-08-2021 to be enrolled in this study
Exclusion criteria
Exclusion criteria: Exclusion criteria adapted for our study were patients with known allergy to study drugs, patient refusal of local anaesthetic block, patients suffering from neurological disorders, psychiatric disorders, mental retardation, uncontrolled hypertension and diabetes mellitus, coagulation or bleeding abnormalities,pregnant women and lactating mothers, patients on adrenergic agonist/antagonist medications and infection at the site of the block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome variables studied were the differences in the duration of the analgesia and the duration of motor and sensory blockTimepoint: Sensory and motor block blockade was assessed every 2 min intervals for the initial 30 min and at 15 minute intervals till completion of surgery and in the first 24 hours of postoperative period | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome will be the differences in the duration of onset of the motor and sensory block, fluctuations in haemodynamic variables like heart rate (HR), mean arterial pressure (MAP),respiratory rate( RR) and arterial oxygen saturation (SaO2), total dose of rescue analgesics administered during the 1st 24 hours of post operative period, Ramsay sedation score, surgeon assessment score and patient satisfaction score and any adverse events and drug-related side effects.Timepoint: At every 5 minute intervals after completion of the block till completion of the surgery and at 30 minute intervals thereafter till 1st 24 hours of post operative period | — |
Countries
India
Contacts
Public ContactDr Ramanareddy MV
Gayatri Vidya Parishad Institute of Health Care and Medical Technology
Outcome results
None listed