Health Condition 1: Q20-Q28- Congenital malformations of the circulatory system
Conditions
Interventions
Intervention1: Thoracic Epidural block: One arm of the study will get thoracic epidural block for analgesia and other arm will get fentanyl opioid intravenous infusion for analgesia, both intraoperati
Sponsors
Army Hospital Research and Referral
Eligibility
Inclusion criteria
Inclusion criteria: Paediatric patients ( <14 yrs) undergoing on pump cardiac surgery at Army Hospital R&R, for various indications will be included in the study
Exclusion criteria
Exclusion criteria: Patient in whom epidural catheter is not inserted due to various reasons ( patient refusal, infection over the spine, coagulation disorders, emergency cases, suprasystemic PAH, any association with syndrome, patients with dysrhythmias, patient on intraââ?¬â??aortic balloon counter pulsation (IABP), and patient on antiplatelet agent, low molecular weight heparin or heparin infusion) will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum levels of cytokine IL6Timepoint: Serum levels of cytokine IL6 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Inflammatory marker (IL6,8,10, TNFalpha, CRP) 2. Metabolic marker (glucose) 3. Endocrine marker (Cortisol) 4. Cardiac marker (Trop I, CKMB) 5. Renal marker (NGAL, renal NIRS) 6. HAemodynamic (HR, IBP) 7. ICU complications (LOS, MV duration, mortality)Timepoint: postoperative (4 hrs, 24 hrs and 48 hrs) | — |
Countries
India
Contacts
Public ContactALOK KUMAR
Army Hospital Research and Referral
Outcome results
None listed